CTCF anticorps

N° du produit ABIN6952397

Cet anticorps Lapin Polyclonal détecte spécifiquement CTCF dans WB, ELISA, IF, ChIP et ChIP-seq. Il présente une réactivité envers Humain.

Aperçu rapide pour CTCF anticorps (ABIN6952397)

Antigène: CTCF (CCCTC-Binding Factor (Zinc Finger Protein) (CTCF))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CTCF est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Chromatin Immunoprecipitation (ChIP), ChIP DNA-Sequencing (ChIP-seq)

Classe de qualité: ChIP-seq Grade

Détail du produit anti-CTCF anticorps

Specificité: Polyclonal antibody raised in rabbit against human CTCF (CCCTC-Binding Factor), using 4 KLH coupled peptides.

Réactivité croisée: Souris

Purification: Peptide affinity purified

Immunogène: synthetic peptide

Information d'application

Indications d'application: ChIP/ChIP-seq 1 μg:ChIP
ELISA 1:10,000
WB 1:1,000
IF 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.5 μg/μL

Buffer: PBS, 0.05 % azide, 0.05 % ProClin300

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur CTCF

Antigène: CTCF (CCCTC-Binding Factor (Zinc Finger Protein) (CTCF))

Autre désignation: CTCF

Sujet: CTCF (UniProt/Swiss-Prot entry P49711) is a transcriptional regulator protein with 11 highly conserved zinc finger domains. By using different combinations of the zinc finger domains, CTCF can bind to different DNA sequences and proteins. As such it can act as both a transcriptional repressor and a transcriptional activator. By binding to transcriptional insulator elements, CTCF can also block communication between enhancers and upstream promoters, thereby regulating imprinted gene expression. CTCF also binds to the H19 imprinting control region and mediates maternally inherited higher-order chromatin conformation to restrict enhancer access to IGF2. Mutations in the CTCF gene have been associated with invasive breast cancers, prostate cancers, and Wilms' tumor.

UniProt: P49711